At the start of a science demonstration, the visiting scientist introduces The Living Brain! This green flashing robot is the most powerful on the planet and it actually has the capability to think for itself. Can Spider-Man keep the threat at bay?
Spider-Man teams up with Captain America to try to foil the Grey Gargoyle's plan of stealing the Super Soldier Serum to create an evil army of Captain Americas.
The members of the Super Hero Squad battle against villains, come to each other's aid during a crisis, and learn how to live together in Super Hero City.