System of diseases of the ear, nose, and throat Volume 2
Charles Henry Burnett
Paperback
(RareBooksClub.com, March 6, 2012)
This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1893 Excerpt: ...quite vascular, containing small round cells, due to a proliferation of the connective tissue and not of the epithelium. The epithelial layer remains unaffected at the beginning, but is afterwards infiltrated with embryonic cells which increase its thickness. It finally disappears, the papillary surface of the dermis becoming a mass of embryonic elements. These elements infiltrate the mucous membrane, and in them are embedded the lupous nodules. Raulin has described this morphological structure as follows. The principal mass is composed of cells richer in protoplasm than the embryonic elements, with a diameter two or three times as large, and having two or three nuclei. The protoplasm is opaque, granular, and of round form, being made up of epithelial cells. Near the centre of the mass are found the giant cells of Friedlander, of oval shape, with prolongations, their protoplasm being granular, and with large oval nuclei near the periphery of the cells. These giant cells are few in number, usually from one to five, and it is in them that the bacillus of Koch has been found. This microbe is exceedingly rare and difficult to find. Koch himself found the bacillus only in the twentyseventh section of one of the specimens examined by him. Gottstein says that in one of the preparations of Ehrlich a bacillus of the size of a tuberclebacillus could be seen in a giant cell. DIAGNOSIS. When laryngeal lupus coincides with, or is preceded by, lupus of the skin, it is not difficult to recognize, since the cutaneous manifestation of the disorder is exceedingly characteristic. Not so when the disease appears primarily upon the larynx: it then becomes quite difficult to make a correct diagnosis. Often the affection exists in the throat before it is even suspected by the kee...